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Package: prank (0.0.170427+dfsg-3)

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prank

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Maintainer:

Original Maintainers:

  • Debian Med Packaging Team (Mail Archive)
  • Manuel Prinz
  • Andreas Tille

External Resources:

Similar packages:

Probabilistic Alignment Kit for DNA, codon and amino-acid sequences

PRANK is a probabilistic multiple alignment program for DNA, codon and amino-acid sequences. It's based on a novel algorithm that treats insertions correctly and avoids over-estimation of the number of deletion events. In addition, PRANK borrows ideas from maximum likelihood methods used in phylogenetics and correctly takes into account the evolutionary distances between sequences. Lastly, PRANK allows for defining a potential structure for sequences to be aligned and then, simultaneously with the alignment, predicts the locations of structural units in the sequences.

PRANK is a command-line program for UNIX-style environments but the same sequence alignment engine is implemented in the graphical program PRANKSTER. In addition to providing a user-friendly interface to those not familiar with Unix systems, PRANKSTER is an alignment browser for alignments saved in the HSAML format. The novel format allows for storing all the information generated by the aligner and the alignment browser is a convenient way to analyse and manipulate the data.

PRANK aims at an evolutionarily correct sequence alignment and often the result looks different from ones generated with other alignment methods. There are, however, cases where the different look is caused by violations of the method's assumptions. To understand why things may go wrong and how to avoid that, read this explanation of differences between PRANK and traditional progressive alignment methods.

Other Packages Related to prank

  • depends
  • recommends
  • suggests
  • dep: libc6 (>= 2.29)
    GNU C Library: Shared libraries
    also a virtual package provided by libc6-udeb
  • dep: libgcc-s1 (>= 3.0)
    GCC support library
  • dep: libstdc++6 (>= 9)
    GNU Standard C++ Library v3
  • enh: t-coffee
    Multiple Sequence Alignment

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Architecture Package Size Installed Size Files
amd64 386.3 kB1196 kB [list of files]